I used to be a close follower of the pharma industry, and you're making it seem like FDA trials happen on molecules and formulations somewhat related to the proposed formulation and then are, like, transitively approved on that hand-wavey basis. This is totally wrong.

For reasons that should be obvious to any engineer that's worked on any kind of even moderately complex system, the molecule that is tested and trialed is the molecule that goes to production.

You don't test "the technology" and then some unrelated other vaccine and then say, there we go, this one's safe.

You test the actual formulation that will go to production. This can't have happened for this yet. The trials are still underway. Unknown risk.

I dunno if you're misinformed or a troll, but that's dangerous stuff to be putting out there.

Vaccines are amazing life-saving tech, and they're safe because of our cultural technologies (FDA trials for e.g.) that make them safe. You can't take all the safety gear out and still get the same safety rating. Doesn't make sense, lol.

We have now had two separate rare-but-serious side effects of different Covid vaccines: the CVT issue with J&J, and the myocarditis issue with the mRNA vaccines in children. It's disingenuous to suggest that the vaccines are "safe" merely because they've been widely administered; even the question of what "safe" means is a far more nuanced question than you're presenting. For children, in particular, two-dose vaccination with the mRNA vaccines is probably a poor risk/benefit profile. We didn't know that until we started dosing enough kids to see the rare side effects.

The phase 3 trials were not powered to detect rare side effects, which is part of the reason that they're still classified as emergency use, and not fully approved.

I am an advocate for vaccination, but it's not right to ignore these issues.

This is true by medicinal standards, but it's also a sleight-of-hand. The AstraZeneca vaccine had a rare side-effect that was right on track to kill more young women in Europe than the virus itself. That's why it was banned. By that standard, I could argue the viral infection is also safe - for young women at least.

I am extremely healthy, have a great diet, and as a farmer, I get plenty of time soaking up vitamin D, a potent inhibitor of covid. The vaccine doesn't make any sense for me to take.

Normal disclaimer, I am a huge, huge believer in vaccines, and am probably more vaccinated (due to travel and other circumstances) than nearly everyone reading this comment. I believe bar none vaccines are the medical technology that has saved the most lives in our history as a species. Big fan of vaccines.

But, vaccines are made safe via clinical trials and long-term studies. These vaccines are wholly new in type, were rushed to market, have liability waivers for those pushing them, and to make things even worse, the manufacturers aren't collecting followup data about adverse events in any kind of systematic way (as they would during a normal phase4). So it seems to me the playbook that gave us generations of safe vaccines that saved billions of lives has been thrown out the window.

No thanks!