Ask HN: Process for application for immigration to the US

As a followup to my questions in (Senior dev, no degree – which countries may accept me?) https://news.ycombinator.com/item?id=6867363

Do i apply for an H-1B via first or apply for jobs that may cover a visa for me?

Very important is that I have a family and want to move us all over together.

What is your recommendations and/or experience?