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0 pointsliveoneggs4mo ago0 comments

Statins also raise your blood sugar and lower your GLP-1, increasing your risk of diabetes?

They also tend to be continued well into old age (off label) despite increasing fall risk, which is way more dangerous to an 80 year old.

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cthalupa4mo ago

A single study showed a single statin reducing GLP-1 levels and ascribed it to gut microbiome changes that could be totally resolved with UDCA supplementation.

If this even ends up being reproduced it at most says there is an easy fix for people taking atorvostatin and that it might be a concern with other statins, but this should be treated with the same health skepticism of any other single study finding.

Not all statins raise blood sugar either - pitavastatin usually shows an improvement in insulin sensitivity.

liveoneggsOP4mo ago

How many doctors are cycling through all the statin classes to find the least-bad option for each patient?

(I'll rant about one guy I know.. was any of this related to statin over perscribing? who can know)

Now that we have your LDL under management isn't it easier to just add metformin and gabapentin into the mix? I mean what are the chances you're not also put on a calcium blocker too?

Now you've got brain fog and sleepiness? weird! we have some modafinil for that but now that you're developing early-stage dementia know that it's progressive.

cthalupa4mo ago

If you go and tell your doctor you're having trouble with a statin, they should have you try a new one, yeah. Some might need to get clued in on pitavastatin, as it only recently went generic and insurance companies really didn't want to approve it before this due to the cost and wide field of generic statins, but it tends to have one of the best profiles when it comes to side effects.

The PKCS9 inhibitor monoclonal antibodies are an option for most people if they show intolerance to multiple statins - insurance will usually relent at that point.

If your doctor isn't willing to work with you to find the medication that works best for you, then find a new doctor.

array_key_first4mo ago

If you have metabolic syndrome (heart disease, diabetes, obesity, hypertension, liver disease etc) then yes, you will take many different drugs. Because these are all complex conditions that must be managed, and that will lower your quality of life and raise your mortality.

It sometimes seems like if you get one, you get the others. That's because all these diseases feed into each other.

j / k navigate · click thread line to collapse

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cthalupa4mo ago

A single study showed a single statin reducing GLP-1 levels and ascribed it to gut microbiome changes that could be totally resolved with UDCA supplementation.

Not all statins raise blood sugar either - pitavastatin usually shows an improvement in insulin sensitivity.

liveoneggsOP4mo ago

How many doctors are cycling through all the statin classes to find the least-bad option for each patient?

(I'll rant about one guy I know.. was any of this related to statin over perscribing? who can know)

Now that we have your LDL under management isn't it easier to just add metformin and gabapentin into the mix? I mean what are the chances you're not also put on a calcium blocker too?

Now you've got brain fog and sleepiness? weird! we have some modafinil for that but now that you're developing early-stage dementia know that it's progressive.

cthalupa4mo ago

The PKCS9 inhibitor monoclonal antibodies are an option for most people if they show intolerance to multiple statins - insurance will usually relent at that point.

If your doctor isn't willing to work with you to find the medication that works best for you, then find a new doctor.

array_key_first4mo ago

It sometimes seems like if you get one, you get the others. That's because all these diseases feed into each other.

j / k navigate · click thread line to collapse