Successful and "make it big" are subjective. Profitable isn't. You either are or you aren't.
I don't work there or know anyone at the company personally, but I'll start the list with one that I remember reading was profitable pretty much right out of the gate: GazeHawk
To me, startups that actually make profit are much more interesting primarily because so many just want to create some buzz then sell out.
What about the big ones Does delicious.com make money? Or is it a loss-leader for Yahoo. Upcoming.org, do they make a dime on this app?
Flickr has pro accounts at $25 a year. But is it enough to be profitable?
And don't get me started on whether Twitter is profitable…
https://spreadsheets.google.com/ccc?key=0AkkhSN3vaY4jdF90b1l...
PG says "We don't know ourselves yet, because it takes so long for startups to exit. But we have a decent idea how many are successful at the next stage after YC-- the number who are either able to raise more after YC, or don't need to because they're profitable (or in very rare cases acquired). I think for the winter 2010 batch the percentage was in the low to mid 80s."
VIA - http://news.ycombinator.com/item?id=1694832
PG previously said "According to our data, 98/145 or 67.6% of companies we funded in s2009 or before are funded and/or profitable and/or acquired."
VIA - http://news.ycombinator.com/item?id=1185345
More resources:
Current list of HN startups and spin-offs?
http://news.ycombinator.com/item?id=1825396
What percentage of YC startups make it and what percentage fail?
http://news.ycombinator.com/item?id=1276356
Spreadsheet listing all YC-Startups, exits etc:
https://spreadsheets.google.com/ccc?key=0AkkhSN3vaY4jdF90b1l...