That makes sense. It has been done before to a degree. For inspiration, look at Net Integrators Nitix appliance [1]. A UNIX system that was easier to configure, self-managing, largely auto-configed, partly self-healing, automatic backups, HA support, had most applications and a UI to integrate their configuration. It was selling well despite being priced above most SOHO servers. As often with good tech, a big firm (IBM) gobbled it up and rolled the tech into their own stack (Lotus).
A stack like you describe with good traits of Nitix-like solutions could be great for businesses not wanting much IT overhead. Might spread like wild fire so long as you don't sell out or balk over patent suits.
[1] http://www.pcmag.com/article2/0,2817,1734766,00.asp