you can pick 2. Also, if you pick performace, 50% of the time you can only pick 1.
Everything is a tradeoff but it's a lot easier to sell something slow than to sell something that doesn't work, and a lot of the performance costs are due to general techniques encoded in these frameworks that reduce bugs.
Another thing is that things do get faster. I think V8 has gotten 10x faster (at least) on real code since its inception. And that's despite JS not having changed.