Exactly. I have a friend who took another anti-depressant in a long search for one that worked that gave her suicidal ideation, which prompted her to go off it immediately.
As I explain the state of the art of these drugs to people, we know that if you poke at the brain with sticks who's ends are shaped in various ways, certain classes of effects will result. But everything beyond that is pure theory/search for a rational mechanism to e.g. explain this to people who aren't comfortable with pragmatic reality.
