It seems to me the more different input devices, the better, because one can quickly switch the input device when it becomes too repetitive. I’m currently experimenting with a vertical mouse (Anchor), a handheld trackball (IMAGE), a handheld touchpad (Perixx), a vertical keyboard (Kinesis Freestyle2), an ergonomic keyboard (Kinesis Advantage), a sitting/standing desk (IKEA) and a sitting ball. The most effective changes seem to be the vertical keyboard, the remote trackball, the new desk and a couple of streching exercises I started doing. While the Advantage does relieve the pinkies in Emacs, it still feels inferior to the vertical Freestyle2 because the forearms are still in a twisted pose. I think I tend to overly cramp my hands and fingers so that I’m experiencing RSI even without overly long working hours.