The only constant is probably that it is still made on a silicon wafer. But even this wafer changed a lot, and I am not talking about its size.
Would you also compare a horse carriage to a Tesla?
I think it would be closer to a comparison between a car engine in the 1900s and one today. Lots of differences, but the basic principles remain the same and if you were to give someone from one time period a part from the other, they'd easily be able to see what it was.
Edit: silicon, not poly silicon. Not sure why I said poly there...
ICs are made of monocrystalline silicon, not polysilicon. There have been massive efforts to understand how to make it cleaner (internal gettering) and how to get wafer mechanics under control (Nitrogen doping). That does not even touch the changes in production technology to go from 10 mm Wafers to 300 mm Wafers. (You just make them larger, right...)
A lot of new concepts and materials have been introduced to ICs during the last decades. Especially since the 130 nm ground rule, lithography has not been the main limiter. Examples: Copper, Tungsten, Diffusion barriers, Silicide, Strained Silicon, High-k, metal gates, finfet, 3d integration etc...
Modern chips also have quite a few more layers (process steps); e.g. IBM's old 0.13μm process supports 8 metal layers, not counting other steps like epitaxial growth and oxides: https://www.mosis.com/vendors/view/ibm/8rf-dm