Win8 IMO is almost irrelevant, the marketshare isn't there to add a MS Store option for me or many others. The corporations haven't and won't hop on. Everyone is (IMO rightly) focused on iOS/Android/web at the moment. Agreed on MSIs, but I'd add the customizable corporate frontend stores should be more powerful and slick than the current method (same appstore for MS desktop and mobile). It's possible once enterprise moves to the MS Store that MS mobile devices make major inroads. For consumers, I think they'll rejoice at Win10, upgrade to it and by default go to the MS Store for security reasons alone. Not to mention auto-updates, same apps as on MS mobile etc.
I'm not pro-MS, I'm actually anti-all-for-profits and a Mozilla fanboy. I just disagree with Eich on a bytecode for the web, he blew it as far as the web being the prime delivery mechanism for apps is concerned. The webstack sucks, it had to go. Too late now.
I understand my view isn't popular at the moment. Especially among webdevs who are most likely to be reading this HN post. Those people have invested heavily in the webapp dream with their time, skills and careers. Anything to the contrary that it was a great idea is going to get downvoted. Regardless, I think this is an accurate reading of the foreseeable future.