Ask HN: Ultimate Work from Anywhere Headphones?

It depends on what you're looking for in size/portability. Personally, I don't mind lugging around big cans. Beyer DT770, Sony MDR-7506, Audio Technica ATH-M50, Sennheiser PX100 are all good options. I've owned all of the above except for the DT770s, but I break headphones a lot, so right now I have AKG K240s which are probably not ideal because they're half-open and will leak a little noise to the surrounding environment.

The 7506s are actually my favorite I think. They're affordable but don't feel cheap. Good isolation. They're very simple looking compared to others but have a unique sound that I miss. Might get another pair soon.

Noise isolation & travel: Shure SE215 earphones. Good quality at a reasonable price. You can coil them up into a zipper baggie to keep them clean, prevent tangling and to reduce the amount of space they take up in your carry-on.

Sound quality & home office: Sennheiser HD485 (which seem to have been replaced in their lineup by the HD558's) Doesn't block any noise, and people can hear what you're listening to. But excellent bass response and they have a long cord. Comfortable for longer wearing sessions.