As much as I am a fan of startups and their founders, this statement seems excessive. In many cases, the financial risks are passed on to either angel investors or VCs (there are some startups funded by the founders' own savings or mortgages, which is a big risk, but there are still many that aren't). I don't see any significant negative consequences to the founders if a startup fails (they're not risking personal injury, bankruptcy, a lifetime of debt or anything else as severe).