The problem is that it's very easy to force a full recalculate of the whole page layout. Whenever you call .offsetHeight or .offsetWidth or .getComputedStyle, you're doing it. The full list of properties is about 2 dozen strong:
http://gent.ilcore.com/2011/03/how-not-to-trigger-layout-in-...
Most web developers don't know this, and so they're actively making their pages slow. Worse, many popular frameworks build this into the library, and so if you use them, there is no way to keep your pages responsive. JQuery, for example, can easily cause 4-5 layouts with a single call to .css; on a mobile phone and a moderately complex page, that's about a second of CPU time.