Of course, it's possible to use things like JSON-Schema to validate your data if you choose to.
> And if you're using structured data in your rapidly prototyped object, why not just a RDBMS in the first place?
Because where's the RDBMS with a "natural" query language that is well-suited to complex, dynamic queries and document structures? How do people model a document store, with the ability to point to differently-shaped data, in an RDBMS without giving up all that safety?