I try not to make prediction that long in the future, because intelligence explosion is likely to happen sooner than that.
http://intelligenceexplosion.com/Once it does, we will likely fall into one of three outcomes: Heaven, Hell, or Annihilation —most likely Annihilation if we're not careful. Any finer point will be moot.
(EDIT: Before you down-vote the singularity crap, please follow the link. The arguments are long, but serious. Machines will take over the world at some point. We just need to ensure they're gentle about it.)