In my experience, real-time CSS feedback is night-and-day from auto-reload feedback. Ever since first trying MacRabbit CSSEdit (now part of Espresso) a few years ago, I've steered clear of preprocessors simply because I can work way more efficiently writing pure CSS in real time than with all of SASS's features and having to save every time I want to see a change.
Real-time CSS and SASS looks like a game changer.