I am fan and follower of the space however I don't use CRM in my daily job.
I think to compete with Salesforces, more 'insightful' organizations are considering the inclusion of the big data aspect of it (whether its a buzz thread of recent that people are all leaning towards).
Lattice Engines, InsideView, etc... adding intelligence behind it. Also sales people hate re-entering information and likes the possibility of scoring sales. CRMs and Gmail CRM Plugins would be brought no-doubt about that but are they actually useful from the sales person's POV? - if you are trying to think whats the next step in innovation for CRMs.