If all you want to do is differentiate and integrate,
then non-standard analysis is probably, for most people,
a faster way to be able to do just that.
Now read on ...Non-standard analysis has been put on a firm, formal footing. Theorems have been proven showing that (largely) it's equivalent to the regular form of analysis. Some things are easier to prove in standard analysis, some things are easier to prove in non-standard analysis, etc, etc.
However, this is only really of use if all you want to do is calculus. If you want to go beyond calculus, almost everything (in this and related areas) is about sequences, limits, limiting processes, functions, and transformations. There, non-standard analysis tends not to help, and unless you've done calculus the standard way, you have to learn all this stuff in an unfamiliar and difficult-to-visualize, abstract area.
One of the main reasons for continuing to learn calculus in the epsilon-delta limiting process manner is exactly because it's not only formally sound, it's also giving you tools for moving beyond the rather limited world of differential calculus.
Speculating wildly from limited experience, it might also be the case that starting people with the non-standard approach in calculus is actually just as confusing. You may find that you really only got the insights you did because you had already struggled with the standard approach, and then were given something that made it all fall into place. Perhaps some people they think the non-standard approach is easier, but in fact it's only because they've actually got the foundations from the other. Just a thought.