It's pretty significant, yes. Eliminating multiple copies of everything got us a 4:1 reduction in memory footprint in OpenLDAP slapd (compared to our BerkeleyDB-based backend). This is another reason we don't spend too much time worrying about data compression and I/O bound workloads - when you've essentially expanded your available space by a factor of 4, you get the same benefits of compression, without wasting any of the memory or CPU time. And when you can fit a 4x larger working set into your space, you find that you need a lot less actual I/Os.