Just to give some perspective, my own cat loves people, strange or familiar, it doesn't matter at all. Take her to the vet in a car though, and she will go mental, crap and pee in the cat carrier, meow and hiss when she gets let outside of it (never does that otherwise) and be extremely edgy for sometimes 2 days afterwards. I wouldn't go as far as saying this is 'cruel' to the kittens, and it's great that the proceedings are donated to an animal shelter, but I'm pretty sure the kittens will not enjoy it nearly as much as the people who get to cuddle with them.