[1]: http://blog.juiceboxmobile.com/2012/11/20/benchmarking-web-f...
Haxe does expose some platform-specific features that help though, such as C# structs and pointers/unsafe code, as well as platform-specific API's for interacting with the garbage collector (e.g. http://api.haxe.org/cpp/vm/Gc.html). You can take advantage of these while still writing cross-platform code with the usual tricks of conditional compilation.
I've never had it remove something that I needed to rely on via the main loop. It's almost always the opposite (it doesn't remove things or doesn't remove them fast enough, and I have to use object pooling, etc.)
Since their goal is to sell the game i think my comment is relevant (maybe harsh by looking at the votes).
"This library includes Haxe externs for Unity and .NET frameworks, generated via the cslibgen utility. It also includes the HUGSWrapper "using" class, which includes various things to work around Haxe/C# translation issues, as well as make working with Unity easier."
