"Adding to the mounting evidence, Hamilton recently discovered that a key gene (called lipid phosphate phosphatase-1 or LPP1) that helps prevent blood clotting and inflammation to keep your cardiovascular system healthy is significantly suppressed when you sit for a few hours. "The shocker was that LPP1 was not impacted by exercise if the muscles were inactive most of the day," Hamilton says. "Pretty scary to say that LPP1 is sensitive to sitting but resistant to exercise."
