I suspect that if you were to actually use a single monitor that was the size of two 22" monitors side-by-side, you'd prefer it. The question then is how much more would you pay for that? I'd like to see the desktop manufacturers we're speaking of in this thread step up with R&D to make larger, better monitors more affordable.

I agree that multi-monitor configurations are great. I just want them to be unnecessary. I previously wrote this elsewhere:

Organizations and individuals alike have historically compensated for this disappointing reality by using multiple monitors, side-by-side. This should have been a short-lived condition--a signal to the manufacturers that larger screens are desired, in order to view and interact with more information at once. But display manufacturers seemingly ignored that signal, and PC manufacturers also looked the other way.