A brief history mostly off the top of my head
1 - reagan didn't care at all about aids until an actor friend of his died of it;
2 - the strong perception within the fda was that reagan didn't care about aids / didn't want anything done about it;
3 - reagan allowed his staff to delete a mention of ryan white from a speech;
4 - reagan didn't mention aids publicly until mid 1987
Writing in the Washington Post in late 1985, Rep. Henry Waxman, D-Los
Angeles, stated: "It is surprising that the president could remain silent as
6,000 Americans died, that he could fail to acknowledge the epidemic's
existence. Perhaps his staff felt he had to, since many of his New Right
supporters have raised money by campaigning against homosexuals." [1]
5 - act-up, amongst others, fought with the fda about not just glacial drug approval processes, but also the fda denying access to experimental therapies even to patients without other therapeutic options;6 - I don't remember this as well, but I believe hiv patients also had to fight the fda for early-ending of clinical trials, because they were insisting that people taking placebos should basically die
So some of this is similar to why many gay people of the right age hate Ed Koch, but an aggressive intervention by the reagan administration might have saved many lives.
[1] http://www.sfgate.com/opinion/openforum/article/Reagan-s-AID...