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0 pointselectromagnetic17y ago0 comments

It also corresponds to what I've read before, that a high-meat (not pure protein, but diets inclusive of bone marrows or organs like liver and stuff generally found in pâtés) and high animal fat diet can almost completely prevent the development of diabetes, and can actually get diabetics off of insulin.

I believe the theory is, is that the body uses insulin to convert glucose to glycogen, AKA 'animal starch', and every other effect (that I'm aware of) it has on the body is not considered good. Example: It promotes triglyceride production from fatty acids (high triglycerides are usually a big factor in heart disease), and decreases the metabolism of fats (I think everyone wants this one high), proteins and reduces gluconeogenesis, which can exacerbate lactose intolerance in some people.

Everything more complex than raw glucose doesn't require insulin. That's why the body largely doesn't react to fructose (which is a result of our ancestry, primates largely live in a symbiosis with the trees they feed off because larger animals like Elephants frequently kill the trees in the process of foraging, but shrieking monkeys tend to stop them) so that we do consume more of it. I think it also helps that foods high in fructose (IE fruits) are generally also high in vitamins. I mean some of the recommended RDA's for vitamin C are actually around 6,000-12,000 mg a day (30,000 mg if you're sick). Basically from what I understand, if you look at our close relatives diets (which are very similar to our ancestors diets) they essentially eat 1:1 ratio of vitamin C (in mg) to kcals. So an adult male should eat 2,500 mg of vitamin C and 2,500 kcals. Incidentally vitamin C is used in the body to produce carnitine, which moves fatty acids into the mitochondria to produce ATP.

Your average goat produces around 13,000 mg of vitamin C in normal health through biosynthesis, which has to make you wonder about WHO's RDA of 45 mg a day if a goat produces 290 times that amount. We, unfortunately don't biosynthesise vitamin C.

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billswift17y ago· 1 in thread

All carbs require insulin. Fructose and complex carbs need other "processing" first though, which spreads out their absorption, reducing spikes in insulin levels.

electromagneticOP17y ago

Actually they don't, carbs are broken down into glucose, fructose and galactose. Glucose, generally, requires insulin to be absorbed by the muscles, liver and fat cells. However Fructose doesn't, the cells then convert it into whatever form necessary, the liver usually converts it into glucose for storage. Yet muscles are capable of using fructose directly.

Glucose can directly be turned into ADP or ATP, or it is converted into Glucose-1-phosphate, which then can either be turned back into glucose or follow the path to be turned into Fructose-6-Phosphate (fructose incidentally directly turns into this). F6P is then converted into triose phosphate, a change that cannot be reversed, and can be directly converted into fat. Fats, when needed, are turned back into triose phosphate and can basically be directly converted into ATP.

Essentially fructose needs less processing than glucose to be readily stored. The aim of the human body is to increase its fat reserves for winter when food becomes scarce. Glucose is readily available and readily usable by the body, but all this depends directly on insulin to get it into cells to be useful. The notable cell that doesn't require insulin are brain cells, however these readily process fructose too.

So it's actually possible to completely remove glucose from the body, in the event it was ever needed then fructose can be back-stepped into glucose-1-phosphate. However, the body can more than adequately produce energy directly from fats, so it would seem extremely rare that the body would need glucose.