"I am reticent to provide exact brand names and instructions because I am not fully convinced of the diet's safety for a physiology different than mine. What if I missed something that's essential for someone of a different race or age group"
But he is interested in actually gathering more data, even if not exactly formally enough for a proper study:
"So…I'll just ship you some of my batch. If you are willing to consume exclusively soylent, and get a CBC, chem panel, and lipid blood test before and after the week and share your results with me it's on the house. Bonus points for getting a psych evaluation before and after. The brain is an organ. I can ship it worldwide but it would be nice if you were in San Francisco so we can meet in person."
Further down on his blog, he has also posted PDF's of his bloodwork.
While he certainly does not have sufficient evidence of general safety and effect, he is aware of that and seems to be actively interested in learning about any flaws in what he's done so far.
> The burdon of evidence should be even greater when it's a non-natural source, as Nassim Taleb argues in Antifragile
This, to me, is ridiculous. A vast range of dangerous poisons are readily avaiable in nature.
I used to pick a lot of mushrooms, and can safely identify perhaps a dozen types common where I grew up. But every year there are people who die agonizing deaths from consuming various nasty toxins because they didn't pay close enough attention to what they picked. And the safety of most mushrooms is unknown - we simply don't have data, and the effects can take a long time to show.
In some cases, popular mushrooms are known to be toxic, such as false morels that contains gyromitrin. They are seemingly safe after boiling. Except there is still gyromitrin in the mushroom, just in small enough quantities that you're ok as long as you don't ingest too much. It's typical to recommend no more than one meal per season, as the poison is stored. But many mushrooms contains compounds we don't know the effect of, and where it is perfectly possible that no effect would be noticeable for a very long time - properly cooked false morels for example, might have no effect on you for years, until you get a bit careless with the cooking (a common way for people to get poisoned by false morels is to stand over the pot while boiling it...)
Nature has an abundant supply of horribly nasty toxic substances that might pass for food for a while.
This is before getting into what "natural" even means.
Everything has to prove its harmlessness. It's just that some things we have a lot of existing data for that at least demonstrates a certain level of safety.
But in the absence of data, I'm no more going to be willing to chew on some random "natural" substance than I'd be willing to ingest some random synthetic substance.