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Second, despite running into it time and again over the years, Searle's Chinese room argument still does not much impress me. It seems to me clear that the setup just hides the difficulty and complexity of understanding in the magical lookup table of the book. Since you've probably encountered this sort of response, as well as the analogy from the Chinese room back to the human brain itself, I'm curious what you find useful and compelling in Searle's argument.
I remain interested in biological approaches to cognition and the potential for insights from brain modelling, but I don't see how it's useful to disparage mathematical and statistical approaches, especially without concrete feats to back up the criticism.