So we start at compiling the codebase (Rust) against MUSL. That way we can run it with FROM scratch images.
If we need more tooling available at runtime, then we look at alpine, but still using MUSL.
If MUSL itself is proving problematic, or if some of the libraries we use need glibc then we can look at using some locked down image.
The cool part about FROM scratch images is that you'll never have to update your base image to address CVEs. Only your software and its (compiled) dependencies.