In 40 years I've never had it, and I'm a Rome citizen.
I'm quite confident most Italians don't even know what's in the recipe besides maybe hearing there's butter.
I did try a month ago to go to the original Alfredo restaurant near via del corso, but the queue and prices (28€ for the pasta alone is crazy) made me go to the restaurant literally on the other side of the street. It was quite clearly a tourist trap.