Even things like universal access to guns was a net positive. It led to the end of feudalism and rise of democracy.
The sad truth is that whenever any one group of people gets a monopoly over an important technology, they use it to exploit/enslave/murder everyone they can. Look at the international news for examples from 2026.
Restrictions on high end biology, chemistry would leave overwhelming number of use cases of LLMs unaffected - no need to ban open weight LLMs. Such restrictions can be even more effective, if it is coupled to researchers getting early access to see the possible problems and have an opportunity to prevent the outbreak or create new vaccines well in advance.
Restrictions are not enabling monopolies. The opposite is true, if a LLM engineered virus or other harmful technology is let loose, public opinion can very quickly swing towards draconian regulation. (see nuclear power after Chernobyl).
I also don't entirely understand your comment, because your latter parts do not follow from your lead. You're 100% right that somebody who's not extremely capable messing with this stuff is overwhelmingly likely to just hurt themselves. And somebody relying on a chatbot to guide them in dealing with this sort of tech? Yeah, they're gonna win a Darwin Award.
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I also think there's an entirely different, yet also compelling argument, against censorship. Local LLMs already exist and are advancing rapidly. There will come a time, probably in the relatively near future, when the state of the art big system and a decent uncensored local system will become practically indistinguishable in terms of capability. So not only will people be able to do this locally, but you lose something big in the process.
The reality is that our interactions with LLMs are 100% being actively surveilled, regardless of privacy promises of the companies involved. At the minimum, every chat is making it's way over to the NSA's Utah data center, one way or the other. Some guy trying to do something significantly malicious using an LLM is little more than a gift to the authorities, but this is only true with centralized/online uncensored services. Push people onto local models to do nefarious stuff, and law enforcement is blinding themselves.
I don't disagree with the rest of your post, but this doesn't seem correct.
I think I'd phrase it that there probably already exist, or will exist, people with the inclination to cause global mass death, but don't have the knowledge or ability to manufacture a virus to achieve this.
Imagine giving the access, to whoever wants it, to a scientist who may not have many fresh insights, but has the advantage of a huge memory containing all the scientific literature in their mind, the standard patterns of deductions, and the ability to work at a very fast pace 24/7. They could identify vulnerabilities in biological mechanisms, just like AI identifies security flaws in code today.
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Regarding hurting themselves, I was not referring to someone who is too dumb to follow lab safety precautions, but someone who has a nihilistic mindset. State actors and militia use weapons to take over and enjoy the power they acquire - they dont want to get killed by a deadly virus(unless they engineer and selectively apply the vaccine before they release the weapon - but this is very hard to keep secret). Someone who is nihilistic wont have such reservations on using the weapon even if it destroys them eventually.
Regarding restrictions on API LLMs leading to use of local LLMs, it is the local LLMs which will be used anyway (once they have the capability). That we live in a mass surveillance envirnoment is common knowledge. The bottleneck, where restrictions can be applied, is not inference but training which requires hundreds of millions of dollars. Chinese scientists have themselves spoken about AI safety concerns and it is indeed a threat to China just like anyone else.
Also, restricting high end weapons ability does not interfere with 99.9% of LLM usage (open-weights or proprietary) - so it need not interfere with business strategy.
There is a big difference between having a large bookshelf of programming language/networking/OS manuals and the ability to generate a functional software product which previously required a hundred or more developers. Even a hundred developers may not be able to find a subtle exploit in code which requires a tedious scan of millions of lines. Computer security hacks can be much less of a problem in comparison to exploits in biology.
Also, even Wikipedia (and public resources in general) have restrictions - there is information dangerous enough to be not published. In the 1930's itself, Szilard (who discovered the chain reaction) and Bohr advocated for restrictions on openly publishing research on uranium fission.
One could argue the opposite conclusion, that technology helps break monopolies, but either view depends on reductionist historical readings. The truth is somewhere in between.