Assuming that the Steam Frame isn't accompanied by a complete change to the current SteamVR experience that hasn't been so much as hinted at, alas, no, SteamVR is full of tiny targets to shoot. I've only ever used the Meta Quest 3S' native UI but the smallest targets there are generally significantly bigger than the smallest targets in the SteamVR UI. On the plus side, once you activate some of those small targets you can do some cursor navigation like a conventional UI, and having that option is a breath of fresh air... but it's completely inconsistent. You experience it as a bonus when it's available because it's not even consistent enough to "miss it when it is gone", let alone for it to be a consistent navigation method.
We may get the obvious eye-tracking upgrade but the targets are still pretty small, it's going to need to be very accurate.
Just the displays and lenses will outweigh glasses considerably and there's nothing to strip back when you're down to display and lenses. Throw in a chassis and head strap and you're pretty far from glasses in weight and ergonomics.
Beoynd 2e has eye tracking. The added mass is just 1 g which is kind of hilarious. You could add 8 visual sensors for pass-through, inside-out tracking and hand tracking, adding maybe 10 g. Compute should probably be on the wired external unit or streamed wirelessly. Having it on-board would probably add less than 50g of mass though, but you also need cooling which is not very easy without adding mass. You could try something like structural heat piping through the headstrap or the battery wire.
Anyway I think it should definitely be doable under 200g, which would be much more comfortable than the current 750-800g.