On the one hand I can appreciate the wisdom of not serving up certain easily abused knowledge on a silver platter. On the other, that prompt (and far worse) is more or less directly answered by Wikipedia's summary of the subject at which point what purpose could the refusal possibly serve?
Perhaps Wikipedia shouldn't list off the precise chemical compositions of various hand grenades as well as various synthesis methods for each of the related compounds but given that we inhabit a world where it does perhaps a more fruitful approach would be to flag conversations that go in a certain direction and then just keep an (automated) eye on things?