At the time he put this rig together, there weren't a lot of open-weight LLMs that could run well on 6x48=288 GB, so it probably wasn't a huge loss. There still aren't, really.
Right now I'm in the process of cramming Blackwell cards into an old DDR4-based Milan server, where the important thing is to be able to run large models at all. The GPU fans alone burn over 400 watts at full throttle.