Here's a quick comparison on just size, clarity and the visibility of inclusions.
A 1ct very good quality stone, E-F, VVS2 or better, no fluorescence - you're looking at a 88% reduction in cost ($700 vs $6,000).
Jump to 2ct and it's $2,300 vs $32,000.
At 3ct, the lab grown is still only $4,200 where the natural at that size starts at $82,000.