I believe they were using their teeth (or lack thereof) to reference their visible meth addiction. See GP, "2) meth is neurodegenerative. heavy users end up with a permanent disability."
Of course the prohibition is what leads to the loss of teeth. Methamphetamine impacts salivation much more commonly and to a greater extent than amphetamine does. But meth is the cheap and accessible option due to the law.
Yeah but if teeth are the worst of it, that's not really the government's problem. The government doesn't prohibit alcohol to prevent liver damage and that's worse than tooth damage. If teeth aren't the worst of it, what was the worst of it?