What things? Looks like an urban myth.
1) Google properties
1a) Chromecast
2) a few web-based games that were really pushing the envelope on web APIs and didn't bother testing on Firefox
3) WebUSB, commonly used for some things like keyboard customization apps
That said, I can only remember two instances of that slightly inconveniencing me in the past, and both times I was inconvenienced by a Google-run website: once upon a time Google Earth refused to work, and once upon a time I couldn't tweak my Google Meet background. Both are no longer the case.
The biggest counterexample I can think of: WebUSB was critical to Chromebooks supporting external devices, but I can see why Safari might not want it. It has Firefox support at last, though.
Kaiser's website works mostly on Firefox. Recently I had to print a "letter" and on Firefox it was blank and printed fine with Chrome.
I don't know if it's still this way, but Google Meet didn't work very well in Firefox, so last year I took all my meetings in Chrome.
These are just what I remember. There are a LOT more.
EDIT: on the UPS thing... it happens when I follow links from gmail in Firefox. Sometimes it wouldn't 404, but I'd see a "..." and it would just stay that way.
EDIT2: for a long time (not anymore), sending Kaiser emails was broken. Hitting enter would warp to the bottom on the page and I'd have to scroll back up to finish typing. They're completely redesigned the website recently and that bug is fixed.