Perturb-MARS: Reading mouse experiments through a human lens (opens in new tab)

If I understand this: the issue is that mouse physiology doesn't really represent human physiology, so they have a mapping from one to the other used to predict what happens in mouse experiments to know what the effect would be on humans?

But this specifically is an AI model (like a LLM) not trained on text, but on specific medical data: "18,963-plex spatial transcriptomics" [0].

Which is a really interesting approach!

[0] https://www.noetik.blog/p/tario-2-a-whole-transcriptome-foun...

Interesting hypotheses but I dont see / missed any preprint or publication of their tools (they show a paper published by a key scientist before he joined their company).

This sounds good but the hard thing for these sweeping experiments is making a discrete, new finding or saying something interesting about an old problem. I’ll be curious to see how they approach that goal at the level of a statement that can withstand peer review

Not to be confused with illumina's MARS-Seq (Massively Parallel scRNA-seq)