BPC157/TB5, IPA/CJC-NoDac, VIP, and Semaglutide (ozempic). Semaglutide was the most effective long term for autoimmune but the others really helped with CCI and other physical ailments. I take a combo of modafinil in the morning and amitryptiline at night as a treatment for dysautonomia and dopamine dysregulation. I started Low Dose Naltrexone and supplemental T3 hormone and this is a good place for most with hEDS to start with.
The worst for me was the chronic fatigue with a strong brain fog component, pretty much all of my symptoms have abated, I still have a residual general anxiety disorder and I still get post exertional malaise so I avoid doing anything that'll take my heart rate over 150. I had pretty much all the standard hEDS symptoms though not as much MCAS and I'm very hypermobile.
