Depreciation, sure. If you’re buying new of course.
Fuel is very much use dependent. I drive very little so having one large nicer (3 years old off a lease return) made the most sense to me when I had to watch the bottom line. Both financially and quality of life.
I filled up the tank on that thing once every 2-3mo at most. Tires cost more due to simply aging out and the rubber compounds not being as spry as they once were. Other than that it was an oil change once a year. It was a Honda so I think the only repair work I did was a $20 relay that failed I was able to self diagnose, over the 13 years I owned it.
Yeah that’s the extreme end - but there is a lot of middle ground before you get into it being cheaper to have a second vehicle. I do now, but that’s due to owning a ridiculous dream weekend car. Maintaining two cars, insuring them, dealing with less space in the garage for other stuff, etc. really is a giant expensive hassle even if both were cheap(ish) used vehicles.
The math switches once you get to “beater” level cars - but I am far removed from the time of my life where I want to deal with actual car repairs due to things breaking unexpectedly. The used car market also isn’t like it was when I was 22 and broke either. Deals are much harder to come by. I value my time and mental energy far more these days as well.
Different strokes for different folks!
If I went back to a single car I’d likely be looking at a PHEV Lexus or similar class vehicle for a bit of luxury plus reliability. I still rarely drive though so it’s a silly expense either way.