The Ryzen AI CPU/GPUs (Ryzan AI 395+ etc) seem to have increasing support -
https://lemonade-server.ai/ now has support for the NPU as well as the combined CPU/GPU (which I guess is a APU but is different to the G series of APUs I think?)
But I'm always interested in first hand experiences of how good is it really - I'm pretty cynical about the idea that AMD actually knows what it takes to build good software end-to-end.