GP works for Netflix. The team that maintains their FreeBSD stack includes FreeBSD committers, as noted in the linked presentation. Bit of a special case.
With that said, I've quickly upgraded to every production release, including .0 releases, on my personal infrastructure boxes for decades and have never been bitten in the ass or spent more than a few minutes making required configuration changes, and have run -CURRENT on development boxes, where it usually works fine.
As a rough analogy, -CURRENT is a bit like Debian Sid. You probably wouldn't run it directly in production, but it's not an unreasonable option if you have the resources to maintain an internal fork (or, for that matter, as the upstream for a downstream distro).
Side note: Netflix support for FreeBSD is one reason I've continued to subscribe through price increases and periods of low use. Keep up the good work!