With multiprocessing, processes are expensive and work hogs each process. You must serialize data twice for IPC, that's expensive and time consuming.
You shouldn't have to break out multiple processes, for example, to do some simple pure-Python math in parallel. It doesn't make sense to use multiple processes for something like that because the actual work you want to do will be overwhelmed by the IPC overhead.
There are also limitations, only some data can be sent to and from multiple processes. Not all of your objects can be serialized for IPC.