(I thought the acknowledgement of life when killing a mosquito was an interesting cultural aspect.)
I did kind of wish that a monastic-like community (or university?) had been presented as seeking more benefit from the City of Mind. Unlike the tribe that asked how to make airplanes (which failed in their military objective), the monks/scholars would train to ask good questions, seeking to restore the land and encourage communication and cooperation among humans. Having even a small bunch of humans interested in such larger issues would have been more optimistic (and perhaps realistic as the existence of an actual Oracle might encourage some people to be scholars, making connections and asking questions). Of course, a ten volume novel would have been even less popular, and LeGuin clearly was motivated to write a more gritty novel.