IMO it would be hypocritical nimbyism if the arsenic warehouse would need to be in someone's living room for those semiconductors to get manufactured.

So you're okay with no refineries after all.

So, no combustion-based private or public transportation, no detergents, no aspirin, paracetamol or ibuprofen.

It would still be possible to drive an EV, though. You could keep it lubricated with whale oil.

Much of the pharmaceutical industry depends on petroleum byproducts.

I agree with your reasoning in principle, but I think it doesn't hold up for California specifically. According to Gemini, 90% of California's population lives in 5% of its land area, and 45-50% of the land is government-owned, much of it being unpopulated wild areas including large parts of the Mojave and Colorado deserts.

The state is large, diverse and already contains vast chunks of unpopulated land. Almost everywhere that isn't near the poles is similar to some part of California.