Many artists would rather blow up their careers than make work solely for business reasons.

There's a huge cadre of content creators and entertainers who are happy to do that, but - as the previous post says - their work is typically entirely forgettable. Even when it's commercially successful.

And successful original creators usually have business managers to deal with "basic economics."

The ideal for most artists is complete creative freedom and an open budget. Not many get there, and not everyone who does get there produces something memorable. But it happens occasionally, and it's usually far more interesting than create-to-market content.