The clearest example is a dependency on a single wealthy nation for military and world policing. It's a good thing for individual countries to be able to project their own foreign policy goals like containing Russia without having to rely on the whims of another country's politics. Even here in Canada we should be able to defend their own arctic border reliably and be able to project power to China/India beyond strongly worded letters.
> I'd be hoping for more international lawyers and trade agreements.
Ignoring the US's recent moves there does seem to be more trade deals than ever between 'middle powers'.
> isolationism is a death sentence
The best way to maintain global relationships is to offer tons of value. Similar to how China can get good trade deals and influence simply because they have so much to offer economically. This isn't just issues of diplomacy.