Yes
There are also gangs making money off human trafficking? Does that make it OK for a corporation to make money off human trafficking as well? And there are companies making money off wars?
When you argue with whataboutism, you can just point to whatever you like, and somehow that is an argument in your favor.
Whataboutism is more like "Side A did bad thing", "oh yeah, what about side B and the bad things they have done". It is more just deflection. While using similar/related issues to inform and contextualize the issue at hand can also be overused or abused, but it is not the same as whataboutism, which is rarely productive.
The point being made then is that clearly there's far more to the picture than just "it's addictive" or "it results in various social ills".
Contrast that with your human trafficking example (definitely qualifies as whataboutism). We have clear reasons to want to outlaw human trafficking. Sometimes we fail to successfully enforce the existing regulations. That (obviously) isn't an argument that we should repeal them.