I'm sorry you've had bad experience working with other people, but in my experience as a developer, having multiple SME's available is indispensable to real alignment and fast development. I've primarily worked in startups, not big companies, and have often worked in healthcare. In healthcare, you get beyond your "I'm a big smart engineer" ego BS and you are willing to listen to the PhD's and MD's that help inform clinical workflows. From my perspective, I would never ask a clinical researcher or a doctor to understand our react app, and they aren't going to ask me to have deep understanding on medical details and clinical workflows. We work together to deliver high quality useful software quickly.