It’s a broad subject. You have the existence of the Philippines itself, which is the only majority Christian nation in Asia, and given it passed from Spain to the USA, this influences everything from US force projection in the Pacific to the prevalence of BPO outsourcing to the sectarian conflicts in Mindanao.

More directly from the trade itself and the silver it brought permanently altered the demographics, flora and fauna of the region. Southern Chinese traders migrated in greater numbers throughout the region, new world fruits and vegetables such as sweet potato and pineapple are introduced. Chinese merchants in the region are producing Christian religious art for export back to the old world, giving rise to a unique hybrid artistic style.[0] The region as a whole becomes more attractive for the Dutch and the British, which had its own set of downstream consequences …

I’m sorry I don’t have a single source that pulls this all together, you would probably need to pick an area and start reading!

[0] https://artsandculture.google.com/story/ivories-from-macau-a...