Humans are very slow. Humans are also squishy, fragile, heavy, and can't take G-forces very well. (Really, at all.)
> the Mark 1 eyeball has some advantages over other optical systems
These are rapidly going away with machine vision research.
> and drones rely on a passive electronic environment
Only ones with a human pilot. The air-to-air drones that will be deployed at the tail end of this decade will be completely autonomous after they receive their orders.
There is ridiculous amount of progress in a-to-a drones at the moment. Very nearly everyone who used to build/design fighters is now concentrating on drones. There will not be a seventh-generation manned fighter, and the sixth-generation ones will be outclassed very rapidly.